Kollicoat® Protect is a combination of water-soluble Kollicoat® IR and polyvinyl alcohol. This instant release coating is highly impermeable to water – making it ideal for moisture-sensitive active ingredients and greatly increasing formulation stability. What’s more, processing is fast and straightforward: this highly flexible film former can be prepared at room temperature, and no plasticizer is required. Thanks to the polymer’s low viscosity, it is possible to create spray suspensions with a solids content of 20 percent – for exceptionally cost-efficient manufacturing processes.
| Molecular Weight | Approx 45000 Daltons |
| Chemical Nature | Owing to the special spray-drying process for Kollicoat® Protect, the polymers are embedded in one another to such an extent that they cannot separate. The powder has good flowability and dissolves rapidly in water. |
| Chemical name: | Polyvinyl alcohol-polyethylene glycol copolymer and polyvinyl alcohol (PVA) |
| CAS-No: | Kollicoat® IR 96734-39-3 Polyvinyl alcohol 9002-89-5 Silicon dioxide 7631-86-9 |
| Description | Together with pigments Kollicoat® Protect gives an excellent moisture protection and taste masking effect. Further to this it can be used as a peroxide-free wet granulation binder or as a pore former in sustained release coatings. |
| HSN Code | 39059100 |
| Regulatory Status | Ph. Eur. monograph with the title “Macrogol Poly(vinylalcohol) Grafted Copolymer is included in Ph. Eur. 6.7. A draft USP/NF monograph entitled “Ethylene Glycol and Vinyl Alcohol Graft Copolymer” is published in Pharmacopeial Forum 35(2). The new NF monograph will be included in USP 33, Supplement 1 |
