Kollidon 25

The modern acetylene chemistry was developed at BASF in the 1930s by Reppe.
One of the many products that emerged from this work are the soluble polyvinylpyrrolidone grades, obtained by radical polymerization of the monomer unit N-vinylpyrrolidone. Kollidon 25 is a medium molecular weight , polymerized in aqueous solution and spray dried polymer. It comes as a white powder with faint ,characteristic odor. The adhesive, film-forming, dispersing and thickening properties of the soluble Kollidon® grades are used in the various modifications of granulation technologies for tablet production, film coating and in the preparation of other dosage forms. The improvement in the solubility of active ingredients brought about by complexation or association, and the thickening effect find use mainly in the manufacture of liquid presentation forms. The grade of Kollidon® that is selected depends mainly on its molecular weight, as this dictates the viscosity, binding effect, the complexation capacity and how readily it is eliminated from the body. Kollidon 25 and Kollidon 30 require binder quantities of 2% and 5% related to the tablet weight. Kollidon 25 is a standard binder used in the pharmaeutical industry as it provides low viscosity of the polymer solution. Kollidon 25 can be provided in a PeroXeal packaging to minimise peroxide formation.