Ludiflash® is a formulation for fast disintegrating solid oral dosage forms.
The formulation of co-processed ingredients consists of three compendial ingredients:
A sugar alcohol, crospovidone and a polymer dispersion based on polyvinyl acetate.
It is tailored to disintegrate readily on the tongue with a pleasant creamy mouth-feel
without a chalky or sandy sensation.
Ludiflash® is suitable for direct compression manufacturing by simply blending the
excipient with the active and a lubricant, and is thus applicable for a very cost efficient
production pathway. Ludiflash® is a white to off-white powder with good flowability. The angle of repose was determined to be ~38 degree.Due to the content of crospovidone and polyvinyl acetate, the product does not dissolve completely in water, nor is it entirely soluble in organic solvents. Ludflash Enhances patient compliance by making drugs pleasant,swallow to take even without water and taste. Due to this , it Increases acceptance of tablets by the very young and elderly.
| Manufacturer | BASF |
| Chemical composition | Ludiflash® consists of D-mannitol, crospovidone, polyvinyl acetate and small amounts of povidone. Polyvinyl acetate is incorporated into the system as Kollicoat® SR 30 D, a polyvinyl acetate dispersion stabilized with povidone |
| Former trade name: | – |
| CAS-No: | D-Mannitol – 69-65-8 ; Crospovidone (Kollidon® CL-SF) 9003-39-8; Polyvinyl acetate (Kollicoat® SR 30 D) 9003-20-7; Povidone (Kollidon® 30) 9003-39-8 |
| Regulatory Status: | sed D-mannitol fully complies to the monographs of the European Pharmacopeia, USP/NF and Japanese Pharmacopeia. |
| Functionalities: | Matrix formers & fillers |
| Packaging Size: | 20KG Fiberboard boxes |
| Country of Origin: | Germany |
