Kollicoat® SR 30 D is a low-viscosity, non-sticky aqueous dispersion of polyvinyl acetate. Whatever the dosage form, this innovative coating releases active ingredients precisely and evenly over a period of time, at any pH. It exhibits a high binding capacity and excellent film-forming properties – simplifying production and ensuring exceptionally flexible coatings. Kollicoat® SR 30 D produces consistent results across multiple formulations: whether deployed as a film coating for extruded or drug-layered pellets, used to coat and com-press multi-particulate single units into tablets, or for granulating and compressing non-erodible sustained-release matrix tablets.
| Molecular Weight | The weight average molecular weight determined with size exclusion chromatography (SEC) – light scattering is approx. 200 000 dalton. |
| Chemical Nature | Polyvinyl acetate stabilized with polyvinylpyrrolidone and sodium lauryl sulfate |
| Application | The main application is for the production of pH-independent sustained-release formulations. In combination with pore-formers the dispersion can also be used for taste masking purposes. |
| Physical Form | 30% Dispersion |
| Solubility | Kollicoat® SR 30 D is miscible with water in any ratio while retaining its milky-white appearance. Mixing the product with ethanol or isopropyl alcohol in a 1 : 5 ratio produces a slightly turbid and somewhat viscous solution; a solution in acetone is more turbid. When organic solvents are added, the polymer precipitates at first, but then dissolves when further solvent is added. Kollicoat® SR 30 D is insoluble in dilute alkaline or acidic solutions. |
| HSN Code | 39059100 |
| Regulatory Status | Kollicoat® SR 30 D meets the requirements of the current monograph for Poly (Vinyl Acetate) Dispersion 30 Per Cent of Ph. Eur. A draft USP/NF monograph entitled Polyvinyl Acetate Dispersion was published in Pharmacopeial Forum 35(1) January 2009 |
