PVP and its derivatives in pharmaceutical production. PVP – also known under the compendial name “povidone” – has a long tradition at BASF and is one of the most interesting and versatile polymers used in the pharmaceutical industry. It helps many of our customers to be even more successful.
Under the registered trade name Kollidon®, PVP is mainly used in tablets as a binder and disintegrant. It thus makes the tablet a true high-tech product: as a binder, it enables the individualactive ingredients of a tablet to form a homogenous entity and as a disintegrant it ensures that the tablets break up in liquid and release the active ingredient quickly.
| Grades | K Value | Molecular Weight | Application |
|---|---|---|---|
| Kollidon 12 PF | 10.2-13.8 | 2000-3000 | Solubilizing agent, dispersant and crystallization inhibitor particularly for injectables. In addition applicable as pore former in solid dosage forms and viscosity enhancer in parenterals |
| Kollidon 17 PF | 15.3-18.0 | 7000-11000 | Solubilizing agent, dispersant and crystallization inhibitor particularly for injectables. In addition applicable as pore former in solid dosage forms and viscosity enhancer in parenterals |
| Kollidon 25 | 22.5-27.0 | 28000-34000 | Binder, pore former, stabilizer, thickener, as solubilizing agent, crystallization inhibitor and many more. And with our trusted quality, it will always serve exactly what you intended it for |
| Kollidon 30 | 27.0-32.4 | 44000-54000 | Binder, pore former, stabilizer, thickener, as solubilizing agent, crystallization inhibitor and many more. And with our trusted quality, it will always serve exactly what you intended it for |
| Kollidon 30 LP | 27.0-32.5 | 44000-54000 | Suitable for peroxide-sensitive active ingredients – due to its built in peroxide protection, Kollidon® 30 LP forms no peroxides for extensive period of time, even after the PeroXeal packaging is opened. Kollidon® 30 LP is therefore particularly suited for the use as binder for peroxide sensitive drugs in solid oral dosage forms. |
| Kollidon 90 F | 81.0-96.3 | 100000-150000 | A highly effective binder, for use as a stabilizer in oral and topical suspensions, as a thickener, and as a hydrophilizing agent or pore-forming agent in medical plastics. |
