Kollitab™ DC 87 L is an all-in-one lactose-based coprocessed excipient designed for direct compression of solid oral dosage forms. As an all-in-one excipient, it contains all the functionalities required for formulating an immediate release tablet: filler, disintegrant, binder and lubricant. Each ingredient in its composition was expertly selected with the end-use in mind. Furthermore, the manufacturing process was designed specifically to reduce chemical and physical instabilities. Kollitab™ DC 87 L is manufactured via aqueous spray drying. A summary of Kollitab™ DC 87 L components :Lactose monohydrate (87% )is a water-soluble filler. Lactose in general has good
compactability, narrow particle size distribution, and provides good blending properties.
• Kollicoat® IR (3%) is a highly soluble, peroxide-free binder. It is commonly used as a film-former, but it also performs extremely well in wet granulation, having similar
or even better binding properties than PVP K30.
• Kollidon® CL-F (9%) is the fine grade of the disintegrant crospovidone. Fine crospovidone particles provide not only fast disintegration, but also excellent compressibility due to their high surface area. Sodium stearyl fumarate (1%) is utilized as a more hydrophilic tablet lubricant than magnesiumstearate. It has a high degree of API compatibility and robustness to over-lubrication, lessening the impact on drug dissolution and tablet processability when blended for long periods of time. Furthermore, it is suited for high-speed, direct compression of tablets
| Manufacturer | BASF |
| Chemical name: | Soluble polyvinylpyrrolidone is also known as povidon(e), povidonum, polyvidone, poly(1-vinyl-2-pyrrolidone) and PVP. |
| Former trade name: | – |
| CAS-No: | – |
| Regulatory Status: | 86.5% Lactose , 3.5 Ethylene Glycol and vinyl alchol graft copolymer, 9% crospovidone, 1 % sodium stearyl fumarate |
| Functionalities: | Matrix formers & fillers |
| Packaging Size: | 60 L Cardboard Box with PE liner |
| Country of Origin: | Germany |
